Developments in laboratory diagnostics for isocyanate asthma
نویسندگان
چکیده
منابع مشابه
Biomarkers Predicting Isocyanate-Induced Asthma
THREE DIISOCYANATES CAN CAUSE OCCUPATIONAL ASTHMA (OA): toluene diisocyanate (TDI), 4,4 diphenylmethane diisocyanate (MDI), and 1,6-hexamethylene diisocyanate (HDI). We analyzed potential biomarkers of isocyanate-induced OA, based on investigated immunologic, genetic, neurogenic, and protein markers, because there is no serological testing method. The prevalence of serum IgG to cytokeratin (CK)...
متن کاملIsocyanate asthma: respiratory symptoms caused by diphenyl-methane di-isocyanate.
Tanser, A. R., Bourke, M. P., and Blandford, A. G. (1973). Thorax, 28, 596-600. Isocyanate asthma: respiratory symptoms caused by diphenyl-methane di-isocyanate. We investigated 57 employees of a factory where diphenyl-methane di-isocyanate (MDI) was used to prepare the materials for making rigid polyurethane foam. Four employees had developed hypersensitivity to MDI. Two had severe, and one mo...
متن کاملIsocyanate asthma: respiratory symptoms due to 1,5-naphthylene di-isocyanate.
Occupationally related asthma developing in three patients due specifically to exposure to 1,5-naphthylene di-isocyanate (NDI), a hot curing agent used in manufacturing rubber, has been confirmed for the first time using bronchial provocation testing. This substance has been thought to be safer than toluene di-isocyanate (TDI) and diphenylmethane di-isocyanate (MDI) because of its relatively hi...
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Laboratory diagnosis of human immunodeficiency virus (HIV) infection is fundamental for detecting and monitoring infection. Many diagnostic tools are available that are based on both detection of HIV-specific antibodies and virus antigen, or nucleic acid. As technology evolves, HIV testing assays are being improved providing better sensitivity and specificity. In this short review, we summarize...
متن کاملOutcome determinants for isocyanate induced occupational asthma among compensation claimants.
OBJECTIVES To compare the outcome of occupational asthma (OA) induced by isocyanates in Ontario (where a surveillance programme for exposed workers has been in place for over 15 years), with the outcome of OA induced by other work agents. METHODS Compensated OA claims during the period 1984-88 in Ontario were retrospectively reviewed in a standardised way. RESULTS 136/235 compensated claims...
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ژورنال
عنوان ژورنال: Current Opinion in Allergy & Clinical Immunology
سال: 2007
ISSN: 1528-4050
DOI: 10.1097/aci.0b013e3280895d22